In Sweden, there are several clinical registries used nationwide to collect real-world patient data during clinical care and routine follow-up in the areas of cardiology, cancer, lung disease, infectious disease, psychiatry and more. These national clinical registries contain a goldmine of information that can be used to complement traditional clinical trial data. Sweden is unique in combining the power of registry data with the rigor of randomized clinical trials (RCT) by pioneering R-RCT, or so-called registry-based randomized clinical trials.
Recently, over 100 participants from industry, academia, and the healthcare sector attended an R-RCT workshop given by Forum Uppsala-Örebro and the Uppsala Clinical Research Center (UCR). The workshop covered Sweden’s national R-RCT recommendations and practical advice on R-RCT study design.